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Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, Thirteenth Edition represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman’s careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease.
Enhanced by a full-color presentation and updated to reflect all critical new developments in drug action and drug-disease interaction, the Thirteenth Edition includes more than 440 color illustrations depicting key principles and actions of specific pathways and therapeutic agents. This edition also includes new chapters on hypertension therapy, myocardial ischemia therapy, treatment of pulmonary arterial hypertension, immunostimulants and vaccines, and treatment of viral hepatitis, along with appendices on prescription order writing, patient compliance, and pharmacokinetics
Features of Goodman and Gilman’s The Pharmacological Basis of Therapeutics 13th Edition.
This edition is enhanced by timely new content:
- NEW chapters including Treatment of Pulmonary Arterial Hypertension, Immunity and Inflammation, Immunoglobulins and Vaccines, and Treatment of Viral Hepatitis
- Expanded coverage of cardiovascular disease, with separate chapters on myocardial ischemia, hypertension, and heart failure.
- Increased emphasis on cellular signaling pathways involved in drug action.
- Summary tables at the end of each chapter that organize drugs discussed in that chapter into relevant categories and detail therapeutic usage, clinical pharmacology, and tips
- Chapter Content Outlines at the beginning of each chapter
- Abbreviation boxes in every chapter to easily identify the abbreviations appearing in that chapter
More than a textbook, Goodman & Gilman’s is a working template for the effective and rational prescribing of drugs in daily practice.
TABLE OF CONTENTS.
Following are the complete chapters of this book given below;
SECTION I: GENERAL PRINCIPLES.
Chapter 1: Drug Invention and the Pharmaceutical Industry
Chapter 2: Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination
Chapter 3: Pharmacodynamics: Molecular Mechanisms of Drug Action
Chapter 4: Drug Toxicity and Poisoning
Chapter 5: Membrane Transporters and Drug Response
Chapter 6: Drug Metabolism
Chapter 7: Pharmacogenetics
SECTION II: NEUROPHARMACOLOGY.
Chapter 8: Neurotransmission: The Autonomic and Somatic Motor Nervous Systems
Chapter 9: Muscarinic Receptor Agonists and Antagonists
Chapter 10: Anticholinesterase Agents
Chapter 11: Nicotine and Agents Acting at the Neuromuscular Junction and Autonomic Ganglia
Chapter 12: Adrenergic Agonists and Antagonists
Chapter 13: 5-Hydroxytryptamine (Serotonin) and Dopamine
Chapter 14: Neurotransmission in the Central Nervous System
Chapter 15: Drug Therapy of Depression and Anxiety Disorders
Chapter 16: Pharmacotherapy of Psychosis and Mania
Chapter 17: Pharmacotherapy of the Epilepsies
Chapter 18: Treatment of Central Nervous System Degenerative Disorders
Chapter 19: Hypnotics and Sedatives
Chapter 20: Opioids, Analgesia, and Pain Management
Chapter 21: General Anesthetics and Therapeutic Gases
Chapter 22: Local Anesthetics
Chapter 23: Ethanol
Chapter 24: Drug Use Disorders and Addiction
SECTION III: MODULATION OF PULMONARY, RENAL, AND CARDIOVASCULAR FUNCTION
Chapter 25: Drugs Affecting Renal Excretory Function
Chapter 26: Renin and Angiotensin
Chapter 27: Treatment of Ischemic Heart Disease
Chapter 28: Treatment of Hypertension
Chapter 29: Therapy of Heart Failure
Chapter 30: Antiarrhythmic Drugs
Chapter 31: Treatment of Pulmonary Arterial Hypertension
Chapter 32: Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs
Chapter 33: Drug Therapy for Dyslipidemias
SECTION IV: INFLAMMATION, IMMUNOMODULATION, AND HEMATOPOIESIS.
Chapter 34: Introduction to Immunity and Inflammation.
Chapter 35: Immunosuppressants and Tolerogens.
Chapter 36: Immune Globulins and Vaccines.
Chapter 37: Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor.
Chapter 38: Pharmacotherapy of Inflammation, Fever, Pain, and Gout.
Chapter 39: Histamine, Bradykinin, and Their Antagonists.
Chapter 40: Pulmonary Pharmacology.
Chapter 41: Hematopoietic Agents: Growth Factors, Minerals, and Vitamins.
SECTION V: HORMONES AND HORMONE ANTAGONISTS
Chapter 42: Introduction to Endocrinology: The Hypothalamic-Pituitary Axis
Chapter 43: Thyroid and Antithyroid Drugs
Chapter 44: Estrogens, Progestins, and the Female Reproductive Tract
Chapter 45: Androgens and the Male Reproductive Tract
Chapter 46: Adrenocorticotropic Hormone, Adrenal Steroids, and the Adrenal Cortex
Chapter 47: Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia
Chapter 48: Agents Affecting Mineral Ion Homeostasis and Bone Turnover
SECTION VI: GASTROINTESTINAL PHARMACOLOGY
Chapter 49: Pharmacotherapy for Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease.
Chapter 50: Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease.
Chapter 51: Pharmacotherapy of Inflammatory Bowel Disease.
SECTION VII: CHEMOTHERAPY OF INFECTIOUS DISEASES
Chapter 52: General Principles of Antimicrobial Therapy.
Chapter 53: Chemotherapy of Malaria
Chapter 54: Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections.
Chapter 55: Chemotherapy of Helminth Infections
Chapter 56: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections.
Chapter 57: Penicillins, Cephalosporins, and Other β-Lactam Antibiotics.
Chapter 58: Aminoglycosides.
Chapter 59: Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents.
Chapter 60: Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy.
Chapter 61: Antifungal Agents.
Chapter 62: Antiviral Agents (Nonretroviral).
Chapter 63: Treatment of Viral Hepatitis (HBV/HCV).
Chapter 64: Antiretroviral Agents and Treatment of HIV Infection.
SECTION VIII: PHARMACOTHERAPY OF NEOPLASTIC DISEASE
Chapter 65: General Principles in the Pharmacotherapy of Cancer
Chapter 66: Cytotoxic Drugs
Chapter 67: Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules
Chapter 68: Hormones and Related Agents in the Therapy of Cancer
SECTION IX: SPECIAL SYSTEMS PHARMACOLOGY
Chapter 69: Ocular Pharmacology
Chapter 70: Dermatological Pharmacology
Chapter 71: Environmental Toxicology: Carcinogens and Heavy Metals
Appendix I: Principles of Prescription Order Writing and Patient Compliance
Appendix II: Design and Optimization of Dosage Regimens: Pharmacokinetic Data
Section X: The Goodman & Gilman Year in Review
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